Rhabdomyoscarcoma PowerPoint Presentation by Dr. Michelle Ghert

Outline

• Introduction
• Epidemiology
• Associated Syndromes
• Clinical Presentation
• Pathological Classification
• Diagnosis and DDx
• Clinical staging and prognosis
• Treatment

• Soft tissue sarcoma in pediatric divided to:
• Rhabdomyosarcoma (40-50%)
• Non-rhabdomyosarcoma (synovial sarcoma, fibrosarcoma, PNET)
• Soft tissue sarcoma common in adult
• Rhabdomyosarcoma: malignant mesenchymal tumor of striated skeletal muscle

Epidemiology

• 3-4% of all child cancer
• 4 cases per million in Canada
• Conmonest STT in patient <20 Y.O
• M:F(I,5:I)
• Two third of cases diagnosed in first 5 years
• Specific risk factor---unknown and most cases are sporadic
• 20% have lung metastases at time of presentation