Rhabdomyoscarcoma PowerPoint Presentation by Dr. Michelle Ghert

Outline

  • Introduction
  • Epidemiology
  • Associated Syndromes
  • Clinical Presentation
  • Pathological Classification
  • Diagnosis and DDx
  • Clinical staging and prognosis
  • Treatment
  • Soft tissue sarcoma in pediatric divided to:
    • Rhabdomyosarcoma (40-50%)
    • Non-rhabdomyosarcoma (synovial sarcoma, fibrosarcoma, PNET)
  • Soft tissue sarcoma common in adult
  • Rhabdomyosarcoma: malignant mesenchymal tumor of striated skeletal muscle

Epidemiology

  • 3-4% of all child cancer
  • 4 cases per million in Canada
  • Conmonest STT in patient <20 Y.O
  • M:F(I,5:I)
  • Two third of cases diagnosed in first 5 years
  • Specific risk factor---unknown and most cases are sporadic
  • 20% have lung metastases at time of presentation

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